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Fisher Scientific Reagent Proteins Haptoglobin Human, 1mg

$3,849.95
For larger quantities: Request a Quote
MFR:
50-230-71
Medex SKU:
FSC-50-230-71
Packing Info:
1/Each
Usually Ships:
1 - 2 Business Days
Freight Quote Button:
False

Description

Features of the Reagent Proteins Haptoglobin Human:




  • Haptoglobin is a glycoprotein which is synthesized in the liver and circulates in the blood. 

  • Haptoglobin is produced typically by hepatocytes but also by other tissues: e.g. skin, lung, and kidney. 

  • It is a positive acute phase protein that binds free hemoglobin and removes it from the circulation to prevent kidney injury, and iron loss following hemolysis.

  • The haptoglobin-hemoglobin complex is subsequently removed by the reticuloendothelial system (generally the spleen). As the reticuloendothelial system removes the haptoglobin-hemoglobin complex from the body, haptoglobin levels are reduced in hemolytic anaemias. 

  • In the course of binding hemoglobin, haptoglobin sequesters the iron inside hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis.